Jack A. Klapper MD

Mile High

Research Center

1155 E. 18th Avenue

Denver, CO 80218

P 303-839-9900

F 303-839-5430

Investigational Research for the Treatment of Alzheimer's Disease

Dr. Klapper is now seeing private patients in clinic

Meet the Doctor

Jack A. Klapper MD

Dr. Klapper was born in 1939 in Wichita, Kansas and moved to Denver when he was 9 years old. After graduating from East High School he attended MIT, following his interest in science. Long weekends spent in the lab made him realize he craved more human contact and made the decision to go to medical school. Upon completion of his MD, he went on to residencies in both Psychiatry and Neurology at the University of Colorado.

He then enlisted in the US Army and served as a Major doing research on the effects of nerve agents. When his service was complete he took a fellowship in Neurology at Queen Square Hospital in London. He started his Neurology practice in Denver in 1974. He has served on the Board of Medical Examiners for the state of Colorado and was the Chief of Internal Medicine at St. Joseph's Hospital. He began doing clinical trials in Neurology in the early 90's. He is currently focused on finding new treatments for Alzheimer's Disease.

Dr. Klapper has been married to his wife Gail for 50 years and has 4 daughters and 7 grandchildren. He is an avid photographer and wildlife enthusiast. He swims and plays tennis whenever possible.

What is Alzheimer's Disease?

Alzheimer's disease: A progressive neurologic disease of the brain that leads to the irreversible loss of neurons and dementia. The clinical hallmarks of Alzheimer's disease are progressive impairment in memory, judgment, decision making, orientation to physical surroundings, and language. A working diagnosis of Alzheimer disease is usually made on the basis of the neurologic examination. A definitive diagnosis can be made only at autopsy. On a cellular level, Alzheimer's disease is characterized by unusual helical protein filaments in nerve cells (neurons) of the brain. These odd twisted filaments are called neurofibrillary tangles. On a functional level, there is degeneration of the cortical regions, especially the frontal and temporal lobes, of the brain.

Alzheimer's disease is the most common of all neurodegenerative diseases. It accounts for about two-thirds of cases of dementia with vascular causes and other neurodegenerative diseases making up most of the rest.

Find out whether you or a loved one qualifies to join one of our studies now on our Getting Started page.

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